The broadcast showed authorities at the scene dealing with the issue as colored smoke filled the air. Cameras captured a moment when stage leader Alberto Bettiol deftly rode his bike through protesters but eventually had to stop.
It appeared that most of the runners were held back to gather and wait for the road to be cleared.
The Tour de France race center said: “The race is neutralized. The race will resume with the same time gaps once the road is clear.”
French climate action group Last Renovation claimed responsibility for Tuesday’s protest.
The statement said the group “can no longer remain a spectator of the ongoing climate catastrophe. We have 989 days left to save our future, our humanity”.
He continues: “Our goal is to force legislation to drastically reduce France’s emissions, starting with energy reform, the area most likely to reconcile social and climate justice today.
“This is our last chance to avoid catastrophic and irreversible consequences: deadly heat, extreme weather events, famines, mass migrations, armed conflicts…and this is for all future generations of humans.”
The incident happened 36 kilometers (22.37 miles) from the finish line in Megeve, France.
Stage 10 of the famous French race has restarted after around 15 minutes of disruption caused by protesters.
CNN has reached out to tour organizers for comment.